Check out all the Nobel Prizes Connected with cyclic AMP
Carl and Gerty Cori’s Nobel prize-winning work on glycogen metabolism (1947 Nobel) inspired a string of Nobel prizes that surround the actions of cAMP.
1971 – Earl Sutherland – discovery of cyclic AMP
1992 – Ed Fisher and Ed Krebs – reversible phosphorylation as a signaling mechanism using cyclic AMP-dependent kinase (PKA)
1994 – Al Gilman and Martin Rodbell – Discovery of Heterotrimeric G proteins
(1998 – Murad, Furchgott and Ignarro – Discovery of cyclic GMP)
2000 – Carlsson, Paul Greengard and Eric Kandel – signaling mechanisms that contribute to learning and memory, including cAMP-dependent CREB activation.
2004 - Linda Buck and Richard Axel – discovery of olfactory receptors that signal through cyclic AMP
2012 – Brian Kobilka and Robert Lefkowitz –For studies of G protein coupled receptors and the structural determination of the Gs-beta-adrenergic receptor complex that stimulates cyclic AMP production by adenylyl cyclase.
1971 – Earl Sutherland – discovery of cyclic AMP
1992 – Ed Fisher and Ed Krebs – reversible phosphorylation as a signaling mechanism using cyclic AMP-dependent kinase (PKA)
1994 – Al Gilman and Martin Rodbell – Discovery of Heterotrimeric G proteins
(1998 – Murad, Furchgott and Ignarro – Discovery of cyclic GMP)
2000 – Carlsson, Paul Greengard and Eric Kandel – signaling mechanisms that contribute to learning and memory, including cAMP-dependent CREB activation.
2004 - Linda Buck and Richard Axel – discovery of olfactory receptors that signal through cyclic AMP
2012 – Brian Kobilka and Robert Lefkowitz –For studies of G protein coupled receptors and the structural determination of the Gs-beta-adrenergic receptor complex that stimulates cyclic AMP production by adenylyl cyclase.
